Trypsin + Chymotrypsin + Diclofenac Tablets

Mechanism

• Trypsin & Chymotrypsin: Proteolytic enzymes that reduce inflammation and edema by breaking down inflammatory mediators.
• Diclofenac Sodium: NSAID that inhibits prostaglandin synthesis, reducing pain and inflammation.
• Combination: Provides synergistic relief in musculoskeletal and post-surgical conditions.

Pharmacokinetics

• Absorption: Diclofenac absorbed in intestine; enzymes absorbed partially intact.
• Distribution: Widely distributed in plasma and tissues.
• Metabolism: Diclofenac metabolized in liver; enzymes metabolized proteolytically.
• Excretion: Primarily via urine and feces.

Side Effects

• Gastrointestinal upset
• Allergic reactions (rare)
• Dizziness or headache

Contraindication

• Hypersensitivity to NSAIDs or enzymes
• Active peptic ulcer disease
• Severe hepatic or renal impairment

Interaction

• Other NSAIDs increase GI risk.
• Anticoagulants may increase bleeding risk.
• Alcohol enhances GI irritation.

Warning and Precautions

• Use under medical supervision in elderly patients.
• Monitor liver and kidney function during therapy.
• Do not exceed recommended dosage.

Dosage

As directed by the Physician.